Translating life science innovations from concept to patient impact
Decades of life science innovation experience, personally available to guide you to the ultimate goal, changing and saving lives.
INTRODUCING LITTLE CUBE CONSULTING
We are living on the precipice of truly life changing technological advancement, yet patient impact is slow or jeopardized.
The healthcare innovation ecosystem is struggling under the pace and weight of change. With over two decades of experience leading lasting change, from innovation ideation to market reality, my focus is on speed in bringing worthy innovations to market and changing patients’ lives.
How are you changing lives?
Reach out for a conversation, consultation or brainstorm for how we can change patient lives together.
jennifer cubino, ma
Professional Background
Over the past two decades, I have worked across the value chain, leading through change and ambiguity in clinical operations, secondary use data, integration of technology into workflows, market strategy, novel diagnostics and novel endpoints, all with a lens on patient and business value, risk assessment and mitigation. I seek to integrate the holistic system, how the pieces assemble into the whole, and at the fingertip level of those on the front lines, flipping with ease between the macro and micro view.
From a leadership perspective, I have extensive training in EQ Leadership, deeply connecting with the work of Daniel Goleman. I have created and implemented leadership development programs, coaching executives so they are confident in leading through change, ambiguity, ultimately building highly agile, high performing teams.
Areas of Expertise
I am an operations person at heart, integrating people, process and technology to drive impact. It is insufficient to build a beautiful strategy without also breathing life into the vision and creating a new reality. Value must be tangible and reproducible.
Hands-On Expertise That I Offer In Support of Your Business Goals
For All Clients
Driving Business Impact
- Strategy and vision development for high value creation
- Reduction in development cost through: investment / portfolio prioritization, operational speed / efficiencies and data strategies
- Effective budget allocation across portfolio / business
- Partnership / JV contract negotiations and equity in partnership
- Vendor / partner qualification and oversight
- Risk assessment and mitigation
- Accountability management for effective decisions and team performance
- Business target setting and critical to success planning
- Governance and decision-making optimization for performance accountability
Effective Boards
- Creation and management of Advisory Boards for impactful feedback
- Development of long-term business vision and targets
- Accountability and oversight
Operational Excellence
- Building and refining operating models to achieve business targets
- Process development / refinement
- Quality: quality system build, refinement, audit preparation, risk assessment
Data and Technology
- Incorporation of AI for human in the loop workflows (operations, governance, visualization, oversight)
- Federation / Trusted Research Environments (TRE) analytics
Partnerships
- Value exchange development, presentation and negotiation
- CRO / third party vendor selection / management
- Partnership deal structure optimization, including protective clauses for risk mitigation
- Partnership performance management, including accountability management, KPIs and balanced scorecard
- Partner journey and corporate branding / reputation management
Executive Coaching
- Building EQ for leadership impact
- Self-awareness: skills for complete self-honesty and reflection, including understanding how others perceive a leader
- Self-management: skills for handling high stress, high ambiguity situations with decisiveness and clarity; growth mindset; handling ladder of inference
- Social awareness: skills for understanding organizational behavior, motivations of others
- Social management: skills for effectively handling conflict, driving high team performance, exceeding targets
- Design thinking: skills for solving complex problems and setting impactful strategies that lead to business results
- Leading through others, including remote teams; driving a highly accountable team
- Giving valuable performance feedback
- Taking decisions, including securing organizational buy-in
- Cross cultural leadership
- Market awareness / strategy
- Change management / influencing
- Executive presence
- Building team diversity
- Effective communication: verbal, written, slides
For Pharma/Biotech
My expertise spans Phase 1 planning through loss of exclusivity
Operational Excellence
- Achieving best in class cycle times in clinical trials
- Protocol design, reducing amendments and site / patient burden
- Clinical trial data flow, inclusive of RBQM / IQRM and third-party vendor data management
- Global RWD access and navigation of market challenges in global scalability
- Data traceability in RWD research
- Data privacy (HIPAA / GDPR) including DPIA development and data privacy / security management
- CDP / IEP integration and evidence strategy for market success
- Clinical trial supply chain / sample management / optimization
- Phase 1 cohort optimization / DSMB safety review optimization
- Patient engagement: recruitment, journey, segmentation, advocacy, expanded access
- Development / growth of global site partnership networks for clinical trials and RWD access, including contractual and regulatory framework; sponsor of choice positioning
Data and Technology
- Infrastructure for secondary use data management: storage, access, analysis
- Conversion to R / Python from SAS
- eCOA / QOL / digital endpoint management
- eConsent
- eTMF
- Tokenization implementation
- CDISC / OMOP data models
- Medidata / Veeva solution implementations
- Structured content authoring
For Health Data and Tech Businesses
My expertise spans from stealth to Series C
Business Impact
- Business model and pricing development and positioning
- Growth vision development with corresponding operating model
- Achieving scalability and profitability
- Fundraise preparation and positioning Series A-C
- Business targets and time horizons, including risk assessments
- Identifying and securing strategic development investors
Go-to-Market
- Market positioning, including identifying competition with novel innovations
- Defining ecosystem and whole product required for client value capture
- Crossing the chasm and achieving hockey stick growth
- Customer experience / customer journey development / refinement
- Development of collateral for sales pitches
- Strategy and KPIs for market success
- Sales process development from lead generation through deal closure
- Contracting optimization
Ecosystem Awareness
- Connectivity in two sided markets, often hospitals / research sites and pharma / biotech
- Integration of the innovation within the current ecosystem, identifying what is impacted and developing the change journey required for value realization
- Ability to represent multiple stakeholder viewpoints: patients, physicians, study coordinators, drug developers, clinical operations
How to Work With Me
My aim is flexibility for clients to find the right-size for the support needed and to evolve our partnership along with the business requirements.
Fractional Executive
Integrate within the team to fulfill a needed operations / strategy / business role for the organization at an agreed upon FTE for a minimum of three months.
Advisory Board Membership
Joining your advisory board for the frequency your business requires.
Unlimited Business Advisory
For a set monthly fee, unlimited advisory support is provided to act as a collaborative sparring partner and advisor to your organization. Deliverables remain the responsibility for your organization, however, unlimited time prioritization is given monthly. Requires a minimum of three months.
Monthly Retainer
For a set monthly fee, reserve a set number of hours of time to support with a myriad of deliverables as your business requires. No minimum commitment.
Project Based
There is a defined need for key scope and deliverables within a set timeline. Based on scope, we agree to a fixed price / fixed scope project.
Time and Materials
Time as used, perhaps to work through the initial stages to define your needs.
I partner with other independent consultants as required to support your business needs. They may be experts in areas such as: regulatory, legal / privacy advisory, data engineering, tech ops or systems validation.
Have Questions? Feeling Inspired? Let’s connect!
Little Cube Consulting is my way of giving back, honoring and paying forward by supporting organizations market success of innovations that change the lives of patients like me.
Because of my personal connection to the power of hope and healing, recovery and joy after being toppled over after a rare disease diagnosis, I am committed to helping innovators bring their ideas to reality, enabling hope and meaningful solutions to patients in need.
My story
Finding my way in the Land of Dystonia
Sometimes life flips us upside down and leaves us gasping, wondering how we will ever be the same. The simple truth, the hard truth, the painful truth, we won’t. Tsunami level change means we can never go back, but instead must create the future, one step at a time. I experienced this daily as I find my way to fully LIVING with a rare movement disorder, cervical dystonia.
Reflections from the Land of Dystonia
Insights of a life science executive living with a rare disease
Amongst Alpine Goddesses
June was an intense alpine month and I somehow managed to be surrounded by women I can only describe as Alpine Goddesses. Imagine high peaks, …
Breathless
If you have ever been even slightly strangled, the most gentle strangle, if you will, you will understand what I write about today. Its …
Surviving Ambiguity
While I have been fortunate to work across the areas of innovation for the bulk of my career, I would be lying if I didn’t acknowledge the anxiety …
My Influences
Daniel Goleman
Goleman’s work is fundamentally about being a kind person that is grounded and authentic in all interactions. I appreciate how his work has challenged me to show up as my best self in all my relationships, business and personal.
Simon Sinek
Sinek inspires us all to think about our Why, our Purpose, and with that purpose to give back to the world. He brings forward the qualities of what makes impactful leaders and reminds us that the strongest leaders work in service to their people.
Brené Brown
Brown’s research into vulnerability and the connectivity to leadership is groundbreaking. I connected with her work when I was seeking my personal executive presence style, and fully embrace her message of authenticity as a leader.
Daniel Pink
Pink’s work on selling and storytelling is unparalleled. He is fast paced and committed to spreading best business practices in succinct and quickly incorporated sizes. For myself, whose authenticity means I am more Trusted Advisor vs. sales person, his guidance deeply resonated.
Geoffrey Moore
Crossing the chasm was my guidebook when I first began building and scaling businesses. The advice is hands-on practical and drives to the business growth target every time.
Clay Christensen
Building innovation within a large organization is wildly different from working within a start-up. Awareness of organizational behavior and protective decision making ensures growth of new innovations even in behemoth organizations.